The rise of nanometers

Three o'clock in the afternoon.

Wang Jinbang was on the hospital bed and pushed into the treatment room.

The anesthesiologist gave him general anesthesia. Before preparing for the operation, the hospital had injected gold nanorods into Wang Jinbang in advance.

After two days of absorption, the targeting compound carries the gold nanorods and is fully absorbed by the cancer cells.

The anesthesiologist whispered to Chang Zhiwen: "Anesthesia is complete."

"Thank you for your hard work." Chang Zhiwen immediately ordered: "Turn on the infrared development system."

"clear."

On the special hospital bed, Wang Jinbang was naked, and several red positioning lights were scanning back and forth on the skinny body.

On the page of the near-infrared light imaging system, a three-dimensional human body is simulated by the computer system.

This is Wang Jinbang's physical condition. His colon cancer is high-grade colon cancer, and it has worsened and shown signs of spreading.

From the three-dimensional simulation layer, it can be clearly observed that in addition to a large group of dense red light spots in the abdomen, sporadic red light spots of cancer cells appear in lymph nodes, liver and other parts. This is a clinical sign of cancer cell metastasis. symptom.

Although there were no problems with gold nanorod photothermal therapy in clinical tests, Chang Zhiwen still did not take it lightly.

"Everyone should go to their respective positions, starting with the cancer cells on the lymph nodes, and gradually eliminate these metastatic cancer cells."

"Copy that." The doctor responsible for controlling the near-infrared light irradiation nodded.

The rescue workers are also on the side, ready to respond to emergencies.

Soon, the first near-infrared light, which has a relatively high power but cannot harm ordinary cells, shines on Wang Jinbang's lymph nodes.

Chang Zhiwen stared at the detection data on the operation page. The system's temperature sensor had detected the local red spots on Wang Jinbang's lymph nodes, and the temperature soared rapidly.

100 degrees Celsius…

150 degrees Celsius…

…

324 degrees Celsius.

This temperature reaches the extreme state, and the cancer cells that "eat" the gold nanorods are instantly killed by the high temperature.

When the temperature reaches 324 degrees Celsius, the heat not only burns the cancer cells to death, but also completely disintegrates the nanostructure of the gold nanorods, causing the gold nanorods to disintegrate into gold atoms.

When the structure of gold nanorods is disintegrated, it also means that this special photothermal conversion structure loses its function. When near-infrared light is irradiated on gold atoms, it will not produce an instant high temperature of several hundred degrees Celsius, preventing normal cells from being heated burning.

And the heat surge at that moment is only limited to the inside of the cancer cells. When the cancer cells are burned to death, the heat transferred will plummet with distance, and it will not seriously affect the surrounding normal cells.

At most, you will feel slightly hot or itchy. This is why general anesthesia is required, because many animals tested showed signs of itching.

This is a stress response that occurs when nerve endings are stimulated during heat transfer.

If the patient is not given general anesthesia, if the patient cannot help but scratch, the accuracy of laser irradiation may be affected.

"Report, the cancer cells in the lymph node area have been cleared."

Chang Zhiwen looked at the various data in the vitality detection system. At present, Wang Jinbang's physical condition was relatively stable. He struck while the iron was hot and said: "The next position is the liver."

"receive."

In order to reduce the physical harm of near-infrared light to patients, the location and time of laser irradiation must be strictly controlled.

The air-conditioning in the operating room did not stop the sweat on the foreheads of the doctors and nurses. They were all highly concentrated, paying attention to every feedback data from the patients.

4:22 p.m.

After more than an hour of killing, the transferred cancer cells in Wang Jinbang's body had been completely burned to death.

But everyone knows that the most dangerous level has arrived.

Since Wang Jinbang's colon cancer has blocked the large intestine, he had a bowel surgery before and also removed part of the tumor, so laser treatment must be done very carefully.

The doctor who operates the laser burns the cancer cells bit by bit, starting from the edge, especially near the blood vessels, and operates with great care.

People are mainly worried about blood vessel rupture, causing severe internal bleeding, and at the same time, they want to save the patient's large intestine.

According to general colon cancer surgery, a simple and crude method can only be used to remove the section of intestine close to the tumor.

The purpose of this is to worry about the remaining cancer cells and have no choice but to cut it off.

The consequence is that the patient's large intestine will lose its working ability in the future, and the patient can only defecate through a catheter, making life very troublesome and embarrassing.

Photothermal therapy with gold nanorods provides a solution to preserve the large intestine. It only kills cancer cells as much as possible, retains normal cells, and then allows the body to repair itself to ensure that the large intestine can continue to work in the future.

After a little bit of killing, about 97% of the colon cancer cells in Wang Jinbang's body had been burned to death, and the remaining cancer cells were adhered to the inner wall of the intestine and around blood vessels.

The sweating operating doctor took a few deep breaths and continued to operate calmly. Chang Zhiwen on the side was staring at the three-dimensional simulation layer and fine-tuning the operation plan from time to time.

Suddenly a small blood vessel ruptured, causing slight bleeding: "Pause, change position..."

"clear."

The laser with a radius of a few millimeters kills the adhering cancer cells bit by bit. The intestine is like a piece of ice jade worth millions, picking out the flaws bit by bit.

"Reduce the laser irradiation range to 0.2 mm."

"receive."

When the laser slowly passes over the lesion, it is only less than 0.5 millimeters away from the adherent large blood vessels. A careless move may cause the patient to suffer massive internal bleeding in an instant.

Time passed by, and it was 6:11 in the evening.

"Huh!" Chang Zhiwen suddenly let out a sigh of relief.

The two operating doctors on the side were exhausted and collapsed on their seats. They looked at the three-dimensional simulation layer and saw that the red light spots had completely disappeared.

And Wang Jinbang's intestine was saved as he wished.

The nurses and emergency doctors on the side were also relieved and handed Chang Zhiwen and others a glucose-sodium chloride solution to replenish electrolytes.

After drinking two bags of sugar and salt water, Chang Zhiwen stood up. Sitting quietly for more than three hours left him with backache and slight numbness in his feet.

"Thank you for your hard work, Head Nurse Wang. Send the patient to the intensive care unit. This week is a critical period, so be careful."

"I will arrange it." The head nurse nodded.

Chang Zhiwen was still a little worried: "If anything happens, please notify me in time."

"clear."

Although physically and mentally exhausted, Chang Zhiwen dragged his heavy body, opened the door of the operating room, and walked towards the anxiously waiting family members outside.

As soon as they saw Chang Zhiwen walking out of the operating room, Yang Haishan and two old people immediately surrounded him: "Doctor, how is my husband's operation going?"

"doctor,……"

"Everyone, the operation was very successful. The patient's cancer cells have been eliminated. The next step is to stay in the hospital for observation for a month, and we will make follow-up arrangements."

After hearing the news, the two old people cried with joy.

However, Yang Haishan was not completely relieved and continued to ask: "Dr. Chang, I heard that this disease is easy to relapse, and you have to wear a bag."

"Ms. Yang, please rest assured that recurrence does exist, but it can still be prevented by insisting on review and diet." Chang Zhiwen continued:

"As for hanging bags, that is an old technology, or there is no other choice. Today's new technology does not require this."

Yang Haishan felt a lot more relaxed. Her body was limp and she slumped down on the bench, with a trace of happiness and tears in her eyes.

Thank you for your support (ω｀)